A Stylet-Driven ICD Lead Intended for Conduction System Pacing IDE Study

Status: Recruiting
Location: See all (34) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This is a prospective, multi-center, global, single-arm, pivotal investigational study designed to evaluate the safety and effectiveness of the CSP ICD Lead in a subject population indicated for ICD or CRT-D therapy. The clinical investigation will enroll up to 414 subjects at up to 70 participating centers from the United States, Canada, Europe, and Asia Pacific.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:

• Subject must meet current clinical practice guidelines for implantation of ICD or CRT-D and will undergo one of the following:

‣ de novo Abbott ICD system implant (single or dual chamber)

⁃ de novo Abbott CRT-D system implant and is intended to also undergo left ventricle coronary sinus lead implant (for patients indicated for CRT-D according to locally approved indications)

• Subject is ≥ 18 years of age or age of legal consent, whichever age is greater.

• Subject is willing to undergo implant defibrillation testing if requested. Subjects with AF in whom defibrillation testing is required must have been on or willing to be on uninterrupted anticoagulation therapy before, during, and after the implant procedure.

• Subject is willing to comply with clinical investigation procedures and agrees to return to clinic for all required follow-up visits, tests, and exams.

• Subject has been informed of the nature of the clinical investigation, agrees to its provisions and has provided a signed written informed consent, approved by the IRB/EC.

Locations
United States
Alabama
Heart Center Research LLC
RECRUITING
Huntsville
Arkansas
Arrhythmia Research Group
RECRUITING
Jonesboro
Arizona
Banner University Medical Center Phoenix
RECRUITING
Phoenix
California
Premier Cardiology, Inc.
RECRUITING
Newport Beach
University of California at San Diego (UCSD) Medical Center
RECRUITING
San Diego
Washington, D.c.
MedStar Washington Hospital Center
RECRUITING
Washington D.c.
Massachusetts
Beth Israel Deaconess Medical Center
RECRUITING
Boston
New York
New York Presbyterian Hospital/Cornell University
RECRUITING
New York
Ohio
The Cleveland Clinic Foundation
RECRUITING
Cleveland
Pennsylvania
Geisinger Medical Center
RECRUITING
Danville
Lancaster General Hospital
RECRUITING
Lancaster
Hospital of the University of Pennsylvania
RECRUITING
Philadelphia
Tennessee
Erlanger Medical Center
RECRUITING
Chattanooga
Virginia
Sentara Norfolk General Hospital
RECRUITING
Norfolk
Other Locations
Australia
Royal Adelaide Hospital
RECRUITING
Adelaide
The Prince Charles Hospital
RECRUITING
Chermside
Monash Health
RECRUITING
Clayton
Princess Alexandra Hospital
RECRUITING
Woolloongabba
Canada
MUHC- Montreal General Hospital
RECRUITING
Montreal
France
CHU Trousseau
RECRUITING
Chambray-lès-tours
Hôpital Pitié Salpetrière
RECRUITING
Paris
CHRU Hopital de Pontchaillou
RECRUITING
Rennes
Hong Kong Special Administrative Region
Prince of Wales Hospital
RECRUITING
Hong Kong
Queen Mary Hospital
RECRUITING
Hong Kong
India
Velammal Medical College Hospital
RECRUITING
Madurai
Max Super Specialty Hospital
RECRUITING
New Delhi
Sree Chitra Tirunal Institute for Medical Sciences & tech.
RECRUITING
Trivandrum
Italy
Ospedale Niguarda Ca'Granda
RECRUITING
Milan
Ospedale S.S. Annunziata
RECRUITING
Taranto
Singapore
Changi General Hospital
RECRUITING
Singapore
National Heart Centre Singapore
RECRUITING
Singapore
Tan Tock Seng Hospital
RECRUITING
Singapore
Spain
Hospital Universitario Virgen de las Nieves
RECRUITING
Granada
Hospital Universitari i Politècnic La Fe
RECRUITING
Valencia
Time Frame
Start Date: 2025-04-11
Estimated Completion Date: 2028-05
Participants
Target number of participants: 414
Treatments
Experimental: Treatment
Subjects undergoing ICD/CRT implant will be implanted with the CSP ICD Lead in the LBBAP location and undergo required electrical testing
Related Therapeutic Areas
Sponsors
Leads: Abbott Medical Devices

This content was sourced from clinicaltrials.gov